Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.

Published

Journal Article

We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes.Participants were drawn from the original and offspring cohorts of the Framingham Heart Study. Lifetime (30-year) risk of CVD was assessed using a modified Kaplan-Meier approach adjusting for the competing risk of death, beginning from age 50 years.Over 30 years, the lifetime risk of CVD among women with diabetes was 54.8% among normal-weight women and 78.8% among obese women. Among normal-weight men with diabetes, the lifetime risk of CVD was 78.6%, whereas it was 86.9% among obese men.The lifetime risk of CVD among individuals with diabetes is high, and this relationship is further accentuated with increasing adiposity.

Full Text

Duke Authors

Cited Authors

  • Fox, CS; Pencina, MJ; Wilson, PWF; Paynter, NP; Vasan, RS; D'Agostino, RB

Published Date

  • August 2008

Published In

Volume / Issue

  • 31 / 8

Start / End Page

  • 1582 - 1584

PubMed ID

  • 18458146

Pubmed Central ID

  • 18458146

Electronic International Standard Serial Number (EISSN)

  • 1935-5548

International Standard Serial Number (ISSN)

  • 0149-5992

Digital Object Identifier (DOI)

  • 10.2337/dc08-0025

Language

  • eng