Drug and alcohol trajectories among adults with schizophrenia: data from the CATIE study.

Journal Article (Journal Article)

OBJECTIVE: The primary aim is to describe drug and alcohol trajectories in adults with schizophrenia. METHOD: Growth mixture models were used to examine disordered and non-disordered use and abstinence in the Clinical Antipsychotic Trials of Intervention Effectiveness study. RESULTS: Five classes - always abstinent; fluctuating use, abuse, and occasional abstinence; occasional (ab)use; stopped (ab)use; abusing - fit best. Overlap exists between always abstinent drug and alcohol classes; less overlap exists across other classes. CONCLUSION: There is heterogeneity in drug and alcohol use among adults with schizophrenia. The lack of overlap between classes, save always abstinent, suggests modeling drug and alcohol use separately.

Full Text

Duke Authors

Cited Authors

  • Van Dorn, RA; Desmarais, SL; Tueller, SJ; Jolley, JM; Johnson, KL; Swartz, MS

Published Date

  • August 2013

Published In

Volume / Issue

  • 148 / 1-3

Start / End Page

  • 126 - 129

PubMed ID

  • 23726721

Pubmed Central ID

  • PMC3732506

Electronic International Standard Serial Number (EISSN)

  • 1573-2509

Digital Object Identifier (DOI)

  • 10.1016/j.schres.2013.05.006


  • eng

Conference Location

  • Netherlands