Elastomeric microparticles for acoustic mediated bioseparations.
Acoustophoresis has been utilized successfully in applications including cell trapping, focusing, and purification. One current limitation of acoustophoresis for cell sorting is the reliance on the inherent physical properties of cells (e.g., compressibility, density) instead of selecting cells based upon biologically relevant surface-presenting antigens. Introducing an acoustophoretic cell sorting approach that allows biochemical specificity may overcome this limitation, thus advancing the value of acoustophoresis approaches for both the basic research and clinical fields.
Johnson, LM; Gao, L; Shields IV, CW; Smith, M; Efimenko, K; Cushing, K; Genzer, J; López, GP
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