Old and new: appropriate dosing for neonatal antifungal drugs in the nursery.

Published

Journal Article (Review)

Candida infections are a source of significant mortality and morbidity in the neonatal intensive care unit. Treatment strategies continue to change as additional antifungals become available and studies in neonates are performed. Amphotericin B deoxycholate has been favored for many years, but fluconazole has the most data supporting its use in neonatal Candida infections and is often employed for prophylaxis as well as treatment. Voriconazole and posaconazole have limited utility in the nursery and are rarely used. The echinocandins are increasingly administered for invasive Candida infections, although higher doses are required in neonates than in older children and adults.

Full Text

Duke Authors

Cited Authors

  • Ericson, J; Manzoni, P; Benjamin, DK

Published Date

  • June 2013

Published In

Volume / Issue

  • 89 Suppl 1 /

Start / End Page

  • S25 - S27

PubMed ID

  • 23809344

Pubmed Central ID

  • 23809344

Electronic International Standard Serial Number (EISSN)

  • 1872-6232

International Standard Serial Number (ISSN)

  • 0378-3782

Digital Object Identifier (DOI)

  • 10.1016/S0378-3782(13)70009-4

Language

  • eng