Blazing a new TRAIL in hematopoietic cell transplantation.
Publication
, Journal Article
Chao, N
Published in: J Clin Invest
June 2013
There is a ying/yang to most biological therapies, and the balance of efficacy versus toxicity is delicate and sometimes difficult to achieve in favor of the patients. When the therapeutic window is wide, these therapies can be used in the majority of patients, but when the therapeutic window is narrow, the decision to proceed must be carefully balanced with a thoughtful risk-benefit analysis. In this issue of the JCI, Ghosh et al. tackle one of the major obstacles in hematopoietic cell transplantation (HCT) technology: balancing the beneficial antitumor effect with the harmful anti-host effect.
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Published In
J Clin Invest
DOI
EISSN
1558-8238
Publication Date
June 2013
Volume
123
Issue
6
Start / End Page
2362 / 2363
Location
United States
Related Subject Headings
- TNF-Related Apoptosis-Inducing Ligand
- T-Lymphocytes
- Immunology
- Humans
- Graft vs Host Disease
- Graft Rejection
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Chao, N. (2013). Blazing a new TRAIL in hematopoietic cell transplantation. J Clin Invest, 123(6), 2362–2363. https://doi.org/10.1172/JCI69909
Chao, Nelson. “Blazing a new TRAIL in hematopoietic cell transplantation.” J Clin Invest 123, no. 6 (June 2013): 2362–63. https://doi.org/10.1172/JCI69909.
Chao N. Blazing a new TRAIL in hematopoietic cell transplantation. J Clin Invest. 2013 Jun;123(6):2362–3.
Chao, Nelson. “Blazing a new TRAIL in hematopoietic cell transplantation.” J Clin Invest, vol. 123, no. 6, June 2013, pp. 2362–63. Pubmed, doi:10.1172/JCI69909.
Chao N. Blazing a new TRAIL in hematopoietic cell transplantation. J Clin Invest. 2013 Jun;123(6):2362–2363.
Published In
J Clin Invest
DOI
EISSN
1558-8238
Publication Date
June 2013
Volume
123
Issue
6
Start / End Page
2362 / 2363
Location
United States
Related Subject Headings
- TNF-Related Apoptosis-Inducing Ligand
- T-Lymphocytes
- Immunology
- Humans
- Graft vs Host Disease
- Graft Rejection
- Animals
- 42 Health sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences