Intensity, chronicity, circumstances, and consequences of HIV-related fatigue: a longitudinal study.


Journal Article

HIV-related fatigue remains the most troubling complaint of seropositive people. Researchers often use tools to measure fatigue that were developed for other patient populations; thus, the measurement of fatigue specific to HIV is needed. This article describes results from the HIV-Related Fatigue Scale (HRFS) including: (a) the variability in intensity and chronicity of HIV-related fatigue, (b) the circumstances surrounding changes in fatigue, (c) the impact of fatigue on activities of daily living (ADLs), and (d) the consequences of HIV-related fatigue. We collected data every 3 months over a 3-year period from 128 people. HIV-related fatigue was chronic and did not appear to remit spontaneously; those who were the most fatigued at the beginning of the study remained the most fatigued over 3 years. Fatigue interfered more with instrumental activities of daily living than basic ADLs; it also interfered with work, family, and social life. Stress and depression increased fatigue.

Full Text

Duke Authors

Cited Authors

  • Barroso, J; Harmon, JL; Madison, JL; Pence, BW

Published Date

  • October 2014

Published In

Volume / Issue

  • 23 / 5

Start / End Page

  • 514 - 528

PubMed ID

  • 23814175

Pubmed Central ID

  • 23814175

Electronic International Standard Serial Number (EISSN)

  • 1552-3799

Digital Object Identifier (DOI)

  • 10.1177/1054773813492998


  • eng

Conference Location

  • United States