Studying recombination with high-throughput sequencing: an educational primer for use with "fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome".

Journal Article (Journal Article)

An article by Singh and colleagues in this issue of GENETICS quantifies variation in recombination rate across a small region of the Drosophila melanogaster genome, providing an opportunity for instructors of genetics to introduce or reinforce important concepts such as recombination and recombination rate variation, genome sequencing, and sequence features of the genome. Additional background information, a detailed explanation of the methods used in this study, and discussion questions are provided.

Full Text

Duke Authors

Cited Authors

  • Heil, CSS; Noor, MAF

Published Date

  • June 2013

Published In

Volume / Issue

  • 194 / 2

Start / End Page

  • 335 - 339

PubMed ID

  • 23733850

Pubmed Central ID

  • PMC3664845

Electronic International Standard Serial Number (EISSN)

  • 1943-2631

International Standard Serial Number (ISSN)

  • 0016-6731

Digital Object Identifier (DOI)

  • 10.1534/genetics.113.150771


  • eng