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Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines.

Publication ,  Journal Article
Valicenti, RK; Thompson, I; Albertsen, P; Davis, BJ; Goldenberg, SL; Wolf, JS; Sartor, O; Klein, E; Hahn, C; Michalski, J; Roach, M ...
Published in: Int J Radiat Oncol Biol Phys
August 1, 2013

PURPOSE: The purpose of this guideline was to provide a clinical framework for the use of radiation therapy after radical prostatectomy as adjuvant or salvage therapy. METHODS AND MATERIALS: A systematic literature review using PubMed, Embase, and Cochrane database was conducted to identify peer-reviewed publications relevant to the use of radiation therapy after prostatectomy. The review yielded 294 articles; these publications were used to create the evidence-based guideline statements. Additional guidance is provided as Clinical Principles when insufficient evidence existed. RESULTS: Guideline statements are provided for patient counseling, use of radiation therapy in the adjuvant and salvage contexts, defining biochemical recurrence, and conducting a restaging evaluation. CONCLUSIONS: Physicians should offer adjuvant radiation therapy to patients with adverse pathologic findings at prostatectomy (ie, seminal vesicle invastion, positive surgical margins, extraprostatic extension) and salvage radiation therapy to patients with prostate-specific antigen (PSA) or local recurrence after prostatectomy in whom there is no evidence of distant metastatic disease. The offer of radiation therapy should be made in the context of a thoughtful discussion of possible short- and long-term side effects of radiation therapy as well as the potential benefits of preventing recurrence. The decision to administer radiation therapy should be made by the patient and the multidisciplinary treatment team with full consideration of the patient's history, values, preferences, quality of life, and functional status. The American Society for Radiation Oncology and American Urological Association websites show this guideline in its entirety, including the full literature review.

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Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

August 1, 2013

Volume

86

Issue

5

Start / End Page

822 / 828

Location

United States

Related Subject Headings

  • Urology
  • United States
  • Societies, Medical
  • Salvage Therapy
  • Radiotherapy, Adjuvant
  • Radiation Oncology
  • Prostatic Neoplasms
  • Prostatectomy
  • Prostate-Specific Antigen
  • Patient Education as Topic
 

Citation

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MLA
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Valicenti, R. K., Thompson, I., Albertsen, P., Davis, B. J., Goldenberg, S. L., Wolf, J. S., … American Society for Radiation Oncology/American Urological Association, . (2013). Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines. Int J Radiat Oncol Biol Phys, 86(5), 822–828. https://doi.org/10.1016/j.ijrobp.2013.05.029
Valicenti, Richard K., Ian Thompson, Peter Albertsen, Brian J. Davis, S Larry Goldenberg, J Stuart Wolf, Oliver Sartor, et al. “Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines.Int J Radiat Oncol Biol Phys 86, no. 5 (August 1, 2013): 822–28. https://doi.org/10.1016/j.ijrobp.2013.05.029.
Valicenti RK, Thompson I, Albertsen P, Davis BJ, Goldenberg SL, Wolf JS, et al. Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines. Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):822–8.
Valicenti, Richard K., et al. “Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines.Int J Radiat Oncol Biol Phys, vol. 86, no. 5, Aug. 2013, pp. 822–28. Pubmed, doi:10.1016/j.ijrobp.2013.05.029.
Valicenti RK, Thompson I, Albertsen P, Davis BJ, Goldenberg SL, Wolf JS, Sartor O, Klein E, Hahn C, Michalski J, Roach M, Faraday MM, American Society for Radiation Oncology/American Urological Association. Adjuvant and salvage radiation therapy after prostatectomy: American Society for Radiation Oncology/American Urological Association guidelines. Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):822–828.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

August 1, 2013

Volume

86

Issue

5

Start / End Page

822 / 828

Location

United States

Related Subject Headings

  • Urology
  • United States
  • Societies, Medical
  • Salvage Therapy
  • Radiotherapy, Adjuvant
  • Radiation Oncology
  • Prostatic Neoplasms
  • Prostatectomy
  • Prostate-Specific Antigen
  • Patient Education as Topic