Sweet nothings: sensing of sugar metabolites controls T cell function.


Journal Article

Signal transduction and metabolism cooperate to control cell fate, but mechanisms that link metabolic substrates to functional decisions are elusive. Now, Chang et al. (2013) in Cell provide a mechanism whereby available sugars dictate metabolic pathways in activated T cells and direct a nonmetabolic regulatory function of glyceraldehyde-3-phosphate dehydrogenase.

Full Text

Duke Authors

Cited Authors

  • Green, DR; Rathmell, J

Published Date

  • July 2, 2013

Published In

Volume / Issue

  • 18 / 1

Start / End Page

  • 7 - 8

PubMed ID

  • 23823473

Pubmed Central ID

  • 23823473

Electronic International Standard Serial Number (EISSN)

  • 1932-7420

Digital Object Identifier (DOI)

  • 10.1016/j.cmet.2013.06.009


  • eng

Conference Location

  • United States