Selective intermolecular amination of C-H bonds at tertiary carbon centers.

Journal Article

C-H insertion: A method for intermolecular amination of tertiary CH bonds is described that uses limiting amounts of substrate and a convenient phenol-derived nitrogen source. Structure-selectivity and mechanistic studies suggest that steric interaction between the substrate and active oxidant is the principal determinant of product selectivity.

Full Text

Duke Authors

Cited Authors

  • Roizen, JL; Zalatan, DN; Du Bois, J

Published Date

  • October 18, 2013

Published In

Volume / Issue

  • 52 / 43

Start / End Page

  • 11343 - 11346

PubMed ID

  • 24000186

Electronic International Standard Serial Number (EISSN)

  • 1521-3773

Digital Object Identifier (DOI)

  • 10.1002/anie.201304238

Language

  • eng

Conference Location

  • Germany