Pharmacological resolution of a multiloculated Candida spp. liver abscess in a preterm neonate.

Journal Article (Journal Article)

We report the case of a 31-week gestational age neonate with Candida albicans sepsis and a hepatic abscess. Diagnosis relied on clinical and radiological signs of sepsis, liver function impairment and culture isolation of Candida spp. from sterile sites. Liver ultrasound documented the presence of a multiloculated abscess. Treatment with micafungin (3 mg/kg/day) resulted in normalization of liver function and inflammatory laboratory values and improvement of clinical condition. After 30 days of treatment, the liver abscess resolved and at the 8-month follow up the infant is doing well. Prompt diagnosis and antifungal treatment avoided surgical drainage and liver surgery in this high-risk neonate.

Full Text

Duke Authors

Cited Authors

  • Picone, S; Manzoni, P; Bedetta, M; Mostert, M; Benjamin, DK; Paolillo, P

Published Date

  • June 2013

Published In

Volume / Issue

  • 89 Suppl 1 /

Start / End Page

  • S47 - S50

PubMed ID

  • 23809351

Electronic International Standard Serial Number (EISSN)

  • 1872-6232

Digital Object Identifier (DOI)

  • 10.1016/S0378-3782(13)70015-X


  • eng

Conference Location

  • Ireland