Drug and alcohol trajectories among adults with schizophrenia: Data from the CATIE study

Journal Article

Objective: The primary aim is to describe drug and alcohol trajectories in adults with schizophrenia. Method: Growth mixture models were used to examine disordered and non-disordered use and abstinence in the Clinical Antipsychotic Trials of Intervention Effectiveness study. Results: Five classes - always abstinent; fluctuating use, abuse, and occasional abstinence; occasional (ab). use; stopped (ab). use; abusing - fit best. Overlap exists between always abstinent drug and alcohol classes; less overlap exists across other classes. Conclusion: There is heterogeneity in drug and alcohol use among adults with schizophrenia. The lack of overlap between classes, save always abstinent, suggests modeling drug and alcohol use separately. © 2013 Elsevier B.V.

Full Text

Duke Authors

Cited Authors

  • Dorn, RAV; Desmarais, SL; Tueller, SJ; Jolley, JM; Johnson, KL; Swartz, MS

Published Date

  • 2013

Published In

Volume / Issue

  • 148 / 1-3

Start / End Page

  • 126 - 129

International Standard Serial Number (ISSN)

  • 0920-9964

Digital Object Identifier (DOI)

  • 10.1016/j.schres.2013.05.006