A new method to predict neural excitation thresholds for applied electric fields

Conference Paper

We have developed a method to predict excitation thresholds of axons based on the response of passive cable models. An expression describing the transmembrane potential induced in passive cables by an applied electric field is presented. Two terms were found to drive the polarization of a node: a source term described by the activating function at the node, and an ohmic term resulting from redistribution of current from sources at other nodes. The expression is used to predict accurately threshold currents, and greatly reduces the computation time necessary to determine the current required to excite a large number of fibers.

Full Text

Duke Authors

Cited Authors

  • Grill, WM; Durand, D; Warman, EN

Published Date

  • January 1, 1992

Published In

Volume / Issue

  • 4 /

Start / End Page

  • 1384 - 1385

International Standard Serial Number (ISSN)

  • 1557-170X

International Standard Book Number 10 (ISBN-10)

  • 0780307852

Digital Object Identifier (DOI)

  • 10.1109/IEMBS.1992.5761841

Citation Source

  • Scopus