Customising PRESAGE® for diverse applications.

Published

Conference Paper

PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/or relative amounts of these constituents can affect the dose sensitivity, post-irradiation stability, and physical properties of the dosimeter. This allows customisation of PRESAGE® to meet application-specific requirements, such as low sensitivity for high dose applications, stability for remote dosimetry, optical clearing for reusability, and tissue-like elasticity for deformable dosimetry. This study evaluates five hard, non-deformable PRESAGE® formulations and six deformable PRESAGE® formulations and characterizes them for dose sensitivity and stability. Results demonstrated sensitivities in the range of 0.0029 - 0.0467 ΔOD/(Gy·cm) for hard formulations and 0.0003 - 0.0056 ΔOD/(Gy·cm) for deformable formulations. Exceptional stability was seen in both standard and low sensitivity non-deformable formulations, with promising applications for remote dosimetry. Deformable formulations exhibited potential for reusability with strong post-irradiation optical clearing. Tensile compression testing of the deformable formulations showed elastic response consistent with soft tissues, with further testing required for direct comparison. These results demonstrate that PRESAGE® dosimeters have the flexibility to be adapted for a wide spectrum of clinical applications.

Full Text

Duke Authors

Cited Authors

  • Juang, T; Newton, J; Niebanck, M; Benning, R; Adamovics, J; Oldham, M

Published Date

  • 2013

Published In

Volume / Issue

  • 444 /

Start / End Page

  • 012029 -

PubMed ID

  • 24567739

Pubmed Central ID

  • 24567739

International Standard Serial Number (ISSN)

  • 1742-6588

Digital Object Identifier (DOI)

  • 10.1088/1742-6596/444/1/012029

Conference Location

  • England