Evaluation of a clinically intuitive quality assurance method.


Conference Paper

There is a pressing need for clinically intuitive quality assurance methods that report metrics of relevance to the likely impact on tumor control of normal tissue injury. This paper presents a preliminary investigation into the accuracy of a novel "transform method" which enables a clinically relevant analysis through dose-volume-histograms (DVHs) and dose overlays on the patient's CT data. The transform method was tested by inducing a series of known mechanical and delivery errors onto simulated 3D dosimetry measurements of six different head-and-neck IMRT treatment plans. Accuracy was then examined through the comparison of the transformed patient dose distributions and the known actual patient dose distributions through dose-volume histograms and normalized dose difference analysis. Through these metrics, the transform method was found to be highly accurate in predicting measured patient dose distributions for these types of errors.

Full Text

Duke Authors

Cited Authors

  • Norris, H; Thomas, A; Oldham, M

Published Date

  • 2013

Published In

Volume / Issue

  • 444 /

Start / End Page

  • 12022 -

PubMed ID

  • 24454519

Pubmed Central ID

  • 24454519

International Standard Serial Number (ISSN)

  • 1742-6588

Digital Object Identifier (DOI)

  • 10.1088/1742-6596/444/1/012022

Conference Location

  • England