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Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy.

Publication ,  Journal Article
Vo-Dinh, T; Fales, AM; Griffin, GD; Khoury, CG; Liu, Y; Ngo, H; Norton, SJ; Register, JK; Wang, H-N; Yuan, H
Published in: Nanoscale
November 2013

This article provides an overview of the development and applications of plasmonics-active nanoprobes in our laboratory for chemical sensing, medical diagnostics and therapy. Molecular Sentinel nanoprobes provide a unique tool for DNA/RNA biomarker detection both in a homogeneous solution or on a chip platform for medical diagnostics. The possibility of combining spectral selectivity and high sensitivity of the surface-enhanced Raman scattering (SERS) process with the inherent molecular specificity of nanoprobes provides an important multiplex diagnostic modality. Gold nanostars can provide an excellent multi-modality platform, combining two-photon luminescence with photothermal therapy as well as Raman imaging with photodynamic therapy. Several examples of optical detection using SERS and photonics-based treatments are presented to illustrate the usefulness and potential of the plasmonic nanoprobes for theranostics, which seamlessly combines diagnostics and therapy.

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Published In

Nanoscale

DOI

EISSN

2040-3372

ISSN

2040-3364

Publication Date

November 2013

Volume

5

Issue

21

Start / End Page

10127 / 10140

Related Subject Headings

  • Spectrum Analysis, Raman
  • Photosensitizing Agents
  • Photochemotherapy
  • Neoplasms
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Humans
  • Gold
  • DNA
  • Biosensing Techniques
 

Citation

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Chicago
ICMJE
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Vo-Dinh, T., Fales, A. M., Griffin, G. D., Khoury, C. G., Liu, Y., Ngo, H., … Yuan, H. (2013). Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy. Nanoscale, 5(21), 10127–10140. https://doi.org/10.1039/c3nr03633b
Vo-Dinh, Tuan, Andrew M. Fales, Guy D. Griffin, Christopher G. Khoury, Yang Liu, Hoan Ngo, Stephen J. Norton, Janna K. Register, Hsin-Neng Wang, and Hsiangkuo Yuan. “Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy.Nanoscale 5, no. 21 (November 2013): 10127–40. https://doi.org/10.1039/c3nr03633b.
Vo-Dinh T, Fales AM, Griffin GD, Khoury CG, Liu Y, Ngo H, et al. Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy. Nanoscale. 2013 Nov;5(21):10127–40.
Vo-Dinh, Tuan, et al. “Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy.Nanoscale, vol. 5, no. 21, Nov. 2013, pp. 10127–40. Epmc, doi:10.1039/c3nr03633b.
Vo-Dinh T, Fales AM, Griffin GD, Khoury CG, Liu Y, Ngo H, Norton SJ, Register JK, Wang H-N, Yuan H. Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy. Nanoscale. 2013 Nov;5(21):10127–10140.
Journal cover image

Published In

Nanoscale

DOI

EISSN

2040-3372

ISSN

2040-3364

Publication Date

November 2013

Volume

5

Issue

21

Start / End Page

10127 / 10140

Related Subject Headings

  • Spectrum Analysis, Raman
  • Photosensitizing Agents
  • Photochemotherapy
  • Neoplasms
  • Nanostructures
  • Nanoscience & Nanotechnology
  • Humans
  • Gold
  • DNA
  • Biosensing Techniques