Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques.
Publication
, Journal Article
Kolski, HK; Hawkins, C; Zatz, M; de Paula, F; Biggar, D; Alman, B; Vajsar, J
Published in: Neuropathology
June 2008
The Western blot technique is currently the standard detection method for suspected limb girdle muscular dystrophy (LGMD) 2A (calpainopathy). This is the first report in the English literature of the successful application of immunohistochemical techniques to support a diagnosis of LGMD 2A. This approach is straightforward and appears to be reasonably specific. We propose that immunohistochemical methods should be re-evaluated for the screening of undiagnosed patients with suspected LGMD 2A.
Duke Scholars
Published In
Neuropathology
DOI
ISSN
0919-6544
Publication Date
June 2008
Volume
28
Issue
3
Start / End Page
264 / 268
Location
Australia
Related Subject Headings
- Polymorphism, Single-Stranded Conformational
- Polymerase Chain Reaction
- Neurology & Neurosurgery
- Muscular Dystrophies, Limb-Girdle
- Muscle Proteins
- Male
- Immunohistochemistry
- Humans
- Child
- Calpain
Citation
APA
Chicago
ICMJE
MLA
NLM
Kolski, H. K., Hawkins, C., Zatz, M., de Paula, F., Biggar, D., Alman, B., & Vajsar, J. (2008). Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques. Neuropathology, 28(3), 264–268. https://doi.org/10.1111/j.1440-1789.2007.00871.x
Kolski, Hanna K., Cynthia Hawkins, Mayana Zatz, Flavia de Paula, Doug Biggar, Ben Alman, and Jiri Vajsar. “Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques.” Neuropathology 28, no. 3 (June 2008): 264–68. https://doi.org/10.1111/j.1440-1789.2007.00871.x.
Kolski HK, Hawkins C, Zatz M, de Paula F, Biggar D, Alman B, et al. Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques. Neuropathology. 2008 Jun;28(3):264–8.
Kolski, Hanna K., et al. “Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques.” Neuropathology, vol. 28, no. 3, June 2008, pp. 264–68. Pubmed, doi:10.1111/j.1440-1789.2007.00871.x.
Kolski HK, Hawkins C, Zatz M, de Paula F, Biggar D, Alman B, Vajsar J. Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques. Neuropathology. 2008 Jun;28(3):264–268.
Published In
Neuropathology
DOI
ISSN
0919-6544
Publication Date
June 2008
Volume
28
Issue
3
Start / End Page
264 / 268
Location
Australia
Related Subject Headings
- Polymorphism, Single-Stranded Conformational
- Polymerase Chain Reaction
- Neurology & Neurosurgery
- Muscular Dystrophies, Limb-Girdle
- Muscle Proteins
- Male
- Immunohistochemistry
- Humans
- Child
- Calpain