Diagnosis of limb-girdle muscular dystrophy 2A by immunohistochemical techniques.

Journal Article (Journal Article)

The Western blot technique is currently the standard detection method for suspected limb girdle muscular dystrophy (LGMD) 2A (calpainopathy). This is the first report in the English literature of the successful application of immunohistochemical techniques to support a diagnosis of LGMD 2A. This approach is straightforward and appears to be reasonably specific. We propose that immunohistochemical methods should be re-evaluated for the screening of undiagnosed patients with suspected LGMD 2A.

Full Text

Duke Authors

Cited Authors

  • Kolski, HK; Hawkins, C; Zatz, M; de Paula, F; Biggar, D; Alman, B; Vajsar, J

Published Date

  • June 2008

Published In

Volume / Issue

  • 28 / 3

Start / End Page

  • 264 - 268

PubMed ID

  • 18031465

International Standard Serial Number (ISSN)

  • 0919-6544

Digital Object Identifier (DOI)

  • 10.1111/j.1440-1789.2007.00871.x


  • eng

Conference Location

  • Australia