Mind over milkshakes: mindsets, not just nutrients, determine ghrelin response.

Journal Article (Journal Article)

Objective

To test whether physiological satiation as measured by the gut peptide ghrelin may vary depending on the mindset in which one approaches consumption of food.

Methods

On 2 separate occasions, participants (n = 46) consumed a 380-calorie milkshake under the pretense that it was either a 620-calorie "indulgent" shake or a 140-calorie "sensible" shake. Ghrelin was measured via intravenous blood samples at 3 time points: baseline (20 min), anticipatory (60 min), and postconsumption (90 min). During the first interval (between 20 and 60 min) participants were asked to view and rate the (misleading) label of the shake. During the second interval (between 60 and 90 min) participants were asked to drink and rate the milkshake.

Results

The mindset of indulgence produced a dramatically steeper decline in ghrelin after consuming the shake, whereas the mindset of sensibility produced a relatively flat ghrelin response. Participants' satiety was consistent with what they believed they were consuming rather than the actual nutritional value of what they consumed.

Conclusions

The effect of food consumption on ghrelin may be psychologically mediated, and mindset meaningfully affects physiological responses to food.

Full Text

Duke Authors

Cited Authors

  • Crum, AJ; Corbin, WR; Brownell, KD; Salovey, P

Published Date

  • July 2011

Published In

Volume / Issue

  • 30 / 4

Start / End Page

  • 424 - 429

PubMed ID

  • 21574706

Electronic International Standard Serial Number (EISSN)

  • 1930-7810

International Standard Serial Number (ISSN)

  • 0278-6133

Digital Object Identifier (DOI)

  • 10.1037/a0023467

Language

  • eng