Hamartoma of the larynx: A report of two cases

Educational Objective: At the conclusion of this presentation, the participants should be able to describe the clinical presentation, histopathologic findings, and management strategies of hamartomas occurring in the larynx. Objectives: Hamartomas of the larynx are extremely rare, we describe two cases, and review the clinical presentation, histopathologic findings and management of this entity. Study Design: A case report and review of the literature. Methods: Case report and Medline search of the term hamartoma of larynx. Results: Hamartomas are defined as a congenital malformation that consists of a focus of mature, locally derived tissue with abnormal histological architecture. Hamartomas affecting the larynx are extremely rare, with less than twenty well-documented cases in the literature. We report the first case in the English language literature of a patient with a laryngeal hamartoma presenting with a vocal cord paralysis secondary to involvement of the recurrent laryngeal nerve. We also report a case of a large supraglottic hamartoma causing airway obstruction and requiring a partial laryngectomy. Conclusions: Hamartomas of the larynx are rare benign entities that can be locally destructive and cause airway obstruction. Two patients are presented showcasing the clinical symptoms, workup, management and subsequent follow up data.

Duke Scholars

Author David W Jang Rhinology and Skull Base Surgery