Prohemostatic agents to prevent perioperative blood loss.

Other Article (Journal Article;Review)

Surgical patients represent a unique group of patients where therapeutic approaches can be preemptively administered. Pharmacologic strategies to prevent or decrease perioperative bleeding function to attenuate inflammatory responses, reduce hemostatic activation, or provide prohemostatic effects to reduce bleeding and the need for allogeneic transfusions. This article will discuss pharmacologic prohemostatic agents (antifibrinolytics, protamine, desmopressin, fibrinogen, purified protein concentrates, recombinant factor VIIa).

Full Text

Duke Authors

Cited Authors

  • Levy, JH; Tanaka, KA

Published Date

  • July 2008

Published In

Volume / Issue

  • 34 / 5

Start / End Page

  • 439 - 444

PubMed ID

  • 18956283

Electronic International Standard Serial Number (EISSN)

  • 1098-9064

Digital Object Identifier (DOI)

  • 10.1055/s-0028-1092873


  • eng

Conference Location

  • United States