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Management of surgical hemostasis: systemic agents.

Publication ,  Journal Article
Levy, JH; Tanaka, KA
Published in: Vascular
2008

Despite improvements in surgical techniques, the risk for perioperative bleeding remains significant. Transfusion of allogeneic red blood cells, platelets, and hemostatic factors remains the mainstay of current therapy strategy for management of perioperative bleeding. Transfusions significantly contribute to perioperative adverse events. Pharmacologic strategies to prevent or decrease perioperative bleeding are also important therapeutic approaches to reduce the need for allogeneic transfusions. This article discusses systemic pharmacologic prohemostatic agents (aprotinin, lysine analogues, protamine, desmopressin, and recombinant factor VIIa).

Duke Scholars

Published In

Vascular

ISSN

1708-5381

Publication Date

2008

Volume

16 Suppl 1

Start / End Page

S14 / S21

Location

England

Related Subject Headings

  • Treatment Outcome
  • Transfusion Reaction
  • Risk Factors
  • Risk Assessment
  • Postoperative Hemorrhage
  • Humans
  • Hemostatics
  • Hemostasis, Surgical
  • Cardiovascular System & Hematology
  • Blood Loss, Surgical
 

Citation

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MLA
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Levy, J. H., & Tanaka, K. A. (2008). Management of surgical hemostasis: systemic agents. Vascular, 16 Suppl 1, S14–S21.
Levy, Jerrold H., and Kenichi A. Tanaka. “Management of surgical hemostasis: systemic agents.Vascular 16 Suppl 1 (2008): S14–21.
Levy JH, Tanaka KA. Management of surgical hemostasis: systemic agents. Vascular. 2008;16 Suppl 1:S14–21.
Levy, Jerrold H., and Kenichi A. Tanaka. “Management of surgical hemostasis: systemic agents.Vascular, vol. 16 Suppl 1, 2008, pp. S14–21.
Levy JH, Tanaka KA. Management of surgical hemostasis: systemic agents. Vascular. 2008;16 Suppl 1:S14–S21.
Journal cover image

Published In

Vascular

ISSN

1708-5381

Publication Date

2008

Volume

16 Suppl 1

Start / End Page

S14 / S21

Location

England

Related Subject Headings

  • Treatment Outcome
  • Transfusion Reaction
  • Risk Factors
  • Risk Assessment
  • Postoperative Hemorrhage
  • Humans
  • Hemostatics
  • Hemostasis, Surgical
  • Cardiovascular System & Hematology
  • Blood Loss, Surgical