The anticoagulated patient: strategies for effective blood loss management.

Other Article (Journal Article;Review)

Anticoagulant therapy is challenging to modern surgical practice because it complicates risks of bleeding and the need for allogeneic blood transfusions. In an aging population, there is extensive use of antiplatelet agents, and patients present for operations receiving these agents. Hemostatic inhibitors are reviewed here, including anticoagulants, platelet inhibitors (clopidogrel), low-molecular-weight heparins, pentasaccharide (fondaparinux), and other factor Xa inhibitors. Agents used to manage bleeding, including aprotinin, lysine analogs, desmopressin, and recombinant factor VIIa, are discussed.

Full Text

Duke Authors

Cited Authors

  • Levy, JH; Tanaka, KA

Published Date

  • October 2007

Published In

Volume / Issue

  • 142 / 4 Suppl

Start / End Page

  • S71 - S77

PubMed ID

  • 18019936

International Standard Serial Number (ISSN)

  • 0039-6060

Digital Object Identifier (DOI)

  • 10.1016/j.surg.2007.06.029


  • eng

Conference Location

  • United States