Effects of protamine on histamine release from human lung.
Publication
, Journal Article
Levy, JH; Faraj, BA; Zaidan, JR; Camp, VM
Published in: Agents Actions
August 1989
Animal mast cell models demonstrate direct histamine release by protamine. Investigators have proposed that protamine also releases histamine in man. We studied the effects of protamine alone and heparin-protamine mixtures on minced lung tissue for evidence of histamine release. We were unable to demonstrate the release of histamine despite positive anti-IgE controls. Nonimmunologic histamine release from human lung appears unlikely as a mechanism for protamine reactions in man.
Duke Scholars
Published In
Agents Actions
DOI
ISSN
0065-4299
Publication Date
August 1989
Volume
28
Issue
1-2
Start / End Page
70 / 72
Location
Switzerland
Related Subject Headings
- Protamines
- Lung
- Immunoglobulin E
- Humans
- Histamine Release
- Heparin
- Antibodies, Anti-Idiotypic
Citation
APA
Chicago
ICMJE
MLA
NLM
Levy, J. H., Faraj, B. A., Zaidan, J. R., & Camp, V. M. (1989). Effects of protamine on histamine release from human lung. Agents Actions, 28(1–2), 70–72. https://doi.org/10.1007/BF02022982
Levy, J. H., B. A. Faraj, J. R. Zaidan, and V. M. Camp. “Effects of protamine on histamine release from human lung.” Agents Actions 28, no. 1–2 (August 1989): 70–72. https://doi.org/10.1007/BF02022982.
Levy JH, Faraj BA, Zaidan JR, Camp VM. Effects of protamine on histamine release from human lung. Agents Actions. 1989 Aug;28(1–2):70–2.
Levy, J. H., et al. “Effects of protamine on histamine release from human lung.” Agents Actions, vol. 28, no. 1–2, Aug. 1989, pp. 70–72. Pubmed, doi:10.1007/BF02022982.
Levy JH, Faraj BA, Zaidan JR, Camp VM. Effects of protamine on histamine release from human lung. Agents Actions. 1989 Aug;28(1–2):70–72.
Published In
Agents Actions
DOI
ISSN
0065-4299
Publication Date
August 1989
Volume
28
Issue
1-2
Start / End Page
70 / 72
Location
Switzerland
Related Subject Headings
- Protamines
- Lung
- Immunoglobulin E
- Humans
- Histamine Release
- Heparin
- Antibodies, Anti-Idiotypic