Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Journal Article (Journal Article;Review)

While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.

Full Text

Duke Authors

Cited Authors

  • Cullen, BR; Cherry, S; tenOever, BR

Published Date

  • October 16, 2013

Published In

Volume / Issue

  • 14 / 4

Start / End Page

  • 374 - 378

PubMed ID

  • 24139396

Electronic International Standard Serial Number (EISSN)

  • 1934-6069

Digital Object Identifier (DOI)

  • 10.1016/j.chom.2013.09.011


  • eng

Conference Location

  • United States