A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.

Journal Article

Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD. Published by Elsevier Ireland Ltd.

Full Text

Duke Authors

Cited Authors

  • Naylor, JC; Dolber, TR; Strauss, JL; Kilts, JD; Strauman, TJ; Bradford, DW; Szabo, ST; Youssef, NA; Connor, KM; Davidson, JRT; Marx, CE

Published Date

  • 2013

Published In

Volume / Issue

  • 206 / 2-3

Start / End Page

  • 318 - 320

International Standard Serial Number (ISSN)

  • 1872-7123

Digital Object Identifier (DOI)

  • 10.1016/j.psychres.2012.11.008