Circulatory diseases and aging
Age patterns of incidence rates of major circulatory diseases (CDs), their time trends, risk factors, and other characteristics capable of contributing to the debates on the role of aging in the deterioration of human health are investigated using standard statistical methods. The need for approaches capable of addressing more sophisticated questions about the connection between CD and aging-related changes in the human organism are discussed. Methods of statistical modeling are considered an efficient tool for studying the effects of the complex interplay between external and internal processes contributing to deterioration of the status of health, well-being, and survival. Their strength, limitations, and perspectives on their application to available data sets are described. © 2008 Copyright © 2008 Elsevier Inc. All rights reserved.
Akushevich, I; Yashin, AI
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