Prolonged Exposure Therapy and Irritable Bowel Syndrome: A Case Study Examining the Impact of a Trauma-Focused Treatment on a Physical Condition.


Journal Article

Previous research has shown that psychological treatments, particularly those employing cognitive techniques, are particularly effective in the treatment of irritable bowel syndrome (IBS). It is presumed that these psychological interventions are effective at ameliorating the IBS by treating an underlying psychological disorder (often an anxiety disorder), which may be contributing to the autonomic reactivity. This case study examined the change in the physical symptoms of IBS for a patient seeking treatment for rape-related PTSD with comorbid conditions of major depression and panic. At posttreatment, the patient no longer met criteria for PTSD, major depression, or panic. In addition, her primary symptom of IBS, diarrhea frequency, was significantly improved. These findings were maintained at 3 and 9 months posttreatment. Implications for the assessment and treatment of IBS patients with PTSD are discussed.

Full Text

Duke Authors

Cited Authors

  • Weaver, TL; Nishith, P; Resick, PA

Published Date

  • January 1, 1998

Published In

Volume / Issue

  • 5 / 1

Start / End Page

  • 103 - 122

PubMed ID

  • 21179387

Pubmed Central ID

  • 21179387

International Standard Serial Number (ISSN)

  • 1077-7229

Digital Object Identifier (DOI)

  • 10.1016/S1077-7229(98)80023-0


  • eng

Conference Location

  • United States