The 4 comments on the review by Resick et al. (2012) of the complex posttraumatic stress disorder (CPTSD) literature highlight important theoretical and conceptual questions about the nature and utility of CPTSD and echo the very questions that motivated the review. We discuss the points raised in the comments, particularly with respect to the definition of CPTSD, its relationship to PTSD, and treatment implications. We suggest that setting high scientific standards for CPTSD research is an optimal way to advance the conceptualization of the construct and the treatment of this population. Published 2012. This article is a US Government work and is in the public domain in the USA.