Does physiologic response to loud tones change following cognitive-behavioral treatment for posttraumatic stress disorder?

Journal Article (Clinical Trial;Journal Article)

This study examined responses to loud tones before and after cognitive-behavioral treatment for posttraumatic stress disorder (PTSD). Seventy-four women in a PTSD treatment outcome study for rape-related (n = 54) or physical assault-related PTSD (n = 20) were assessed in an auditory loud tone paradigm. Assessments were conducted before and after a 6-week period of cognitive-behavioral therapy. Physiologic responses to loud tones included heart rate (HR), skin conductance (SC), and eye-blink electromyogram (EMG). Groups were formed based upon treatment outcome and included a treatment responder group (no PTSD at posttreatment) and a nonresponder group (PTSD-positive at posttreatment). Treatment was successful for 53 of 74 women (72%) and unsuccessful for 21 women (28%). Responders and nonresponders were not significantly different from each other at pretreatment on the main outcome variables. Treatment responders showed a significant reduction in loud tone-related EMG, HR, and SC responses from pre- to posttreatment (partial η(2) = .24, .31, and .36, respectively; all p < .001) and the EMG and HR responses were significantly smaller than nonresponders at posttreatment (partial η(2) = .11, p = .004 and .19, p < .001, respectively). Successful cognitive-behavioral treatment of PTSD is associated with a quantifiable reduction in physiological responding to loud tones.

Full Text

Duke Authors

Cited Authors

  • Griffin, MG; Resick, PA; Galovski, TE

Published Date

  • February 2012

Published In

Volume / Issue

  • 25 / 1

Start / End Page

  • 25 - 32

PubMed ID

  • 22354505

Pubmed Central ID

  • PMC3336195

Electronic International Standard Serial Number (EISSN)

  • 1573-6598

Digital Object Identifier (DOI)

  • 10.1002/jts.21667


  • eng

Conference Location

  • United States