Cryotherapy of the Prostate


Book Section

Cryosurgery represents a recognized option for the treatment of prostate cancer. Herein we discuss the principles of cryobiology and their implications in modern cryosurgery, review the indications for primary and salvage cryotherapy, as well as summarize perioperative, functional, and oncologic outcomes of the procedure. In the primary setting cryoablation achieves biochemical disease-free survival (bDFS) rates as high as 89.9%, whereas in the salvage setting long-term data show a consistent bDFS rate of over 50%. Cryosurgery is a minimally invasive procedure and complications are typically minor and transient in both the primary and salvage settings. Future developments involve targeted focal therapy whereby healthy prostate tissue is spared with potential reduced morbidity and better preservation of quality of life. © 2012 Blackwell Publishing Ltd.

Full Text

Duke Authors

Cited Authors

  • Tsivian, M; Polascik, TJ

Published Date

  • January 5, 2012

Volume / Issue

  • 2 /

Book Title

  • Smith's Textbook of Endourology: 3rd Edition

Start / End Page

  • 1406 - 1415

International Standard Book Number 10 (ISBN-10)

  • 1444335545

International Standard Book Number 13 (ISBN-13)

  • 9781444335545

Digital Object Identifier (DOI)

  • 10.1002/9781444345148.ch116

Citation Source

  • Scopus