Biology of the vascularized fibular graft
In the practice of orthopedics, bone grafting is a common procedure used to enhance the regeneration of bone and lead to the restoration of skeletal integrity. Bony regeneration is needed to reconstruct a wide variety of traumatic, developmental, degenerative, and neoplastic disorders that affect the skeletal system. The source of bone for grafting has evolved over the past two centuries to include autogenous cancellous or cortical, allogenic frozen, freeze-dried, or processed cortical, corticocancellous, and cancellous grafts, and demineralized bone matrix. Recently, synthetic or engineered bone graft substitutes have also been approved for use. Although this chapter concentrates on the autogenous vascularized fibular graft, a brief review of the history and basic science of bone grafting will serve as an introduction. © 2005 Humana Press Inc.
Joneschild, E; Urbaniak, JR
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