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Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese.

Publication ,  Journal Article
Adams, TD; Pendleton, RC; Strong, MB; Kolotkin, RL; Walker, JM; Litwin, SE; Berjaoui, WK; LaMonte, MJ; Cloward, TV; Avelar, E; Owan, TE ...
Published in: Obesity (Silver Spring)
January 2010

Favorable health outcomes at 2 years postbariatric surgery have been reported. With exception of the Swedish Obesity Subjects (SOS) study, these studies have been surgical case series, comparison of surgery types, or surgery patients compared to subjects enrolled in planned nonsurgical intervention. This study measured gastric bypass effectiveness when compared to two separate severely obese groups not participating in designed weight-loss intervention. Three groups of severely obese subjects (N = 1,156, BMI >or= 35 kg/m(2)) were studied: gastric bypass subjects (n = 420), subjects seeking gastric bypass but did not have surgery (n = 415), and population-based subjects not seeking surgery (n = 321). Participants were studied at baseline and 2 years. Quantitative outcome measures as well as prevalence, incidence, and resolution rates of categorical health outcome variables were determined. All quantitative variables (BMI, blood pressure, lipids, diabetes-related variables, resting metabolic rate (RMR), sleep apnea, and health-related quality of life) improved significantly in the gastric bypass group compared with each comparative group (all P < 0.0001, except for diastolic blood pressure and the short form (SF-36) health survey mental component score at P < 0.01). Diabetes, dyslipidemia, and hypertension resolved much more frequently in the gastric bypass group than in the comparative groups (all P < 0.001). In the surgical group, beneficial changes of almost all quantitative variables correlated significantly with the decrease in BMI. We conclude that Roux-en-Y gastric bypass surgery when compared to severely obese groups not enrolled in planned weight-loss intervention was highly effective for weight loss, improved health-related quality of life, and resolution of major obesity-associated complications measured at 2 years.

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Published In

Obesity (Silver Spring)

DOI

EISSN

1930-739X

Publication Date

January 2010

Volume

18

Issue

1

Start / End Page

121 / 130

Location

United States

Related Subject Headings

  • Weight Loss
  • Treatment Outcome
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Regression Analysis
  • Quality of Life
  • Obesity
  • Middle Aged
  • Male
  • Humans
 

Citation

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Adams, T. D., Pendleton, R. C., Strong, M. B., Kolotkin, R. L., Walker, J. M., Litwin, S. E., … Hunt, S. C. (2010). Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity (Silver Spring), 18(1), 121–130. https://doi.org/10.1038/oby.2009.178
Adams, Ted D., Robert C. Pendleton, Michael B. Strong, Ronette L. Kolotkin, James M. Walker, Sheldon E. Litwin, Wael K. Berjaoui, et al. “Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese.Obesity (Silver Spring) 18, no. 1 (January 2010): 121–30. https://doi.org/10.1038/oby.2009.178.
Adams TD, Pendleton RC, Strong MB, Kolotkin RL, Walker JM, Litwin SE, et al. Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity (Silver Spring). 2010 Jan;18(1):121–30.
Adams, Ted D., et al. “Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese.Obesity (Silver Spring), vol. 18, no. 1, Jan. 2010, pp. 121–30. Pubmed, doi:10.1038/oby.2009.178.
Adams TD, Pendleton RC, Strong MB, Kolotkin RL, Walker JM, Litwin SE, Berjaoui WK, LaMonte MJ, Cloward TV, Avelar E, Owan TE, Nuttall RT, Gress RE, Crosby RD, Hopkins PN, Brinton EA, Rosamond WD, Wiebke GA, Yanowitz FG, Farney RJ, Halverson RC, Simper SC, Smith SC, Hunt SC. Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese. Obesity (Silver Spring). 2010 Jan;18(1):121–130.
Journal cover image

Published In

Obesity (Silver Spring)

DOI

EISSN

1930-739X

Publication Date

January 2010

Volume

18

Issue

1

Start / End Page

121 / 130

Location

United States

Related Subject Headings

  • Weight Loss
  • Treatment Outcome
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Regression Analysis
  • Quality of Life
  • Obesity
  • Middle Aged
  • Male
  • Humans