1 H, 13 C and 15 N backbone and side-chain resonance assignments of Drosophila melanogaster Ssu72


Journal Article

Ssu72 helps regulate transcription and co-transcriptional mRNA processing by dephosphorylating serine residues at the 5th position in the heptad repeats of the C-terminal domain of RNA polymerase II. Here we use multidimensional, multinuclear NMR experiments to assign the backbone and side-chain resonances of the 23 kDa Ssu72 from Drosophila melanogaster in the phosphate-bound state, and use NMR titrations to examine the phosphate-binding properties of three active site mutants. © 2011 Springer Science+Business Media B.V.

Full Text

Duke Authors

Cited Authors

  • Werner-Allen, JW; Zhou, P

Published Date

  • April 1, 2012

Published In

Volume / Issue

  • 6 / 1

Start / End Page

  • 57 - 61

Electronic International Standard Serial Number (EISSN)

  • 1874-270X

International Standard Serial Number (ISSN)

  • 1874-2718

Digital Object Identifier (DOI)

  • 10.1007/s12104-011-9325-2

Citation Source

  • Scopus