Heparitin sulfates (heparan sulfates) of atherosclerosis-susceptible and atherosclerosis-resistant pigeon aortas.


Journal Article

Electrophoretic mobilities of heparitin sulfates (HS) from the thoracic aorta and the celiac bifurcation of atherosclerosis-susceptible White Carneau and atherosclerosis-resistant Show Racer pigeons at four ages were examined. Atherosclerosis-susceptible White Carneau aortas contain, in addition to their normal HS component, a variant type of HS (HS') in pre, early- and moderately-atherosclerotic celiac foci which is not found in the thoracic regions of either breed or in Show Racer celiac foci at any age. These findings are interpreted to suggest a role of HS' in the pathogenesis of atherosclerosis and to propose an explanation for atherosclerotic susceptibility and resistance in pigeons.

Full Text

Cited Authors

  • Curwen, KD; Smith, SC

Published Date

  • May 1, 1977

Published In

Volume / Issue

  • 27 / 1

Start / End Page

  • 113 - 117

PubMed ID

  • 140692

Pubmed Central ID

  • 140692

Electronic International Standard Serial Number (EISSN)

  • 1879-1484

International Standard Serial Number (ISSN)

  • 0021-9150

Digital Object Identifier (DOI)

  • 10.1016/0021-9150(77)90031-4


  • eng