Setting an agenda for comparative effectiveness systematic reviews in CKD care.

Journal Article (Letter)

Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews. We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance. Among 46 topics identified, stakeholders nominated 18 as 'high' priority. Most pertained to strategies to slow disease progression, including: (a) treat proteinuria, (b) improve access to care, (c) treat hypertension, (d) use health information technology, and (e) implement dietary strategies. Most (15 of 18) topics had been previously studied with two or more randomized controlled trials, indicating feasibility of rigorous systematic reviews. Chronic kidney disease topics rated by stakeholders as 'high priority' are varied in scope and may lead to quality systematic reviews impacting practice and policy.

Full Text

Duke Authors

Cited Authors

  • Crews, DC; Greer, RC; Fadrowski, JJ; Choi, MJ; Doggett, D; Segal, JB; Fawole, KA; Crawford, PR; Boulware, LE

Published Date

  • August 1, 2012

Published In

Volume / Issue

  • 13 /

Start / End Page

  • 74 -

PubMed ID

  • 22853705

Pubmed Central ID

  • PMC3472164

Electronic International Standard Serial Number (EISSN)

  • 1471-2369

Digital Object Identifier (DOI)

  • 10.1186/1471-2369-13-74


  • eng

Conference Location

  • England