Contemplating genetic feedback regarding lung cancer susceptibility.
Journal Article (Journal Article)
Background and purpose
We examined three theoretical models (self-enhancement theory, consistency theory, and a combined model) for understanding how expectations and test result favorability influence smokers' desire for a retest following hypothetical genetic test results.Method
College smokers (N = 128) read a brochure describing a biomarker for lung cancer (the GSTM1 gene) then reported whether they thought they had the gene (indicating lower lung cancer risk) or were missing the gene (indicating higher lung cancer risk). Participants then reported whether they would get retested if they received favorable GSTM1 results versus unfavorable GSTM1 results.Results
Participants were most likely to want a retest, suggesting rejection of the results, if they expected favorable news yet received unfavorable news.Conclusion
The findings supported the combined model such that smokers expressed greatest interest in a retest when they imagined genetic risk feedback that challenges both enhancement and consistency motives.Full Text
Duke Authors
Cited Authors
- Shepperd, JA; Novell, CA; O'Neill, SC; Docherty, SL; Sanderson, SC; McBride, CM; Lipkus, IM
Published Date
- June 2014
Published In
Volume / Issue
- 47 / 3
Start / End Page
- 395 - 403
PubMed ID
- 24222509
Pubmed Central ID
- PMC4008648
Electronic International Standard Serial Number (EISSN)
- 1532-4796
International Standard Serial Number (ISSN)
- 0883-6612
Digital Object Identifier (DOI)
- 10.1007/s12160-013-9561-z
Language
- eng