Chemoprevention of prostate cancer.


Journal Article (Review)

Large prospective randomized trials, such as the Prostate Cancer Prevention Trial (PCPT), Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial, and Selenium and Vitamin E Cancer Prevention Trial (SELECT), have provided practitioners with considerable data regarding methods of treatment and prevention of prostate cancer. The best-studied medications for prevention are 5 alpha-reductase inhibitors. Their efficacy and side effects are well characterized. Other medications, dietary nutrients, and supplements have not been as well studied and generally do not demonstrate efficacy for disease prevention with an acceptable level of evidence.

Full Text

Cited Authors

  • Vemana, G; Hamilton, RJ; Andriole, GL; Freedland, SJ

Published Date

  • January 2014

Published In

Volume / Issue

  • 65 /

Start / End Page

  • 111 - 123

PubMed ID

  • 24188663

Pubmed Central ID

  • 24188663

Electronic International Standard Serial Number (EISSN)

  • 1545-326X

International Standard Serial Number (ISSN)

  • 0066-4219

Digital Object Identifier (DOI)

  • 10.1146/annurev-med-121211-091759


  • eng