Localization of brachytherapy seeds in MRI by deconvolution.

Journal Article (Journal Article)

MRI has the potential to be used as a preferred imaging method for brachytherapy during the seed insertion and post-surgery evaluation. However, the brachytherapy seeds usually appear dark in the MRI magnitude images. Previously, we have developed a method based on susceptibility mapping to generate positive contrast of the seeds, which allows improved seed localization. In this paper, we propose a new method to localize the seeds by deconvolution using a seed kernel (i.e. the calculated magnetic field surrounding a seed). The deconvolution is solved using a regularized L1 minimization. Results from simulated and experimental data sets show that the seeds can be identified and localized using the proposed method more precisely.

Full Text

Duke Authors

Cited Authors

  • Dong, Y; Chang, Z; Whitehead, G; Ji, J

Published Date

  • 2013

Published In

  • Annu Int Conf Ieee Eng Med Biol Soc

Volume / Issue

  • 2013 /

Start / End Page

  • 2960 - 2963

PubMed ID

  • 24110348

Electronic International Standard Serial Number (EISSN)

  • 2694-0604

Digital Object Identifier (DOI)

  • 10.1109/EMBC.2013.6610161


  • eng

Conference Location

  • United States