Antithrombotic Strategies in Patients Undergoing Elective Percutaneous Coronary Intervention
The goals of antithrombotic therapy during percutaneous coronary intervention are to mitigate thrombotic complications associated with iatrogenic plaque disruption from the angioplasty balloon or stent and embolization of thrombotic material from procedural equipment. Available therapies are directed against thrombin and platelets and evidence-based regimens include combinations of unfractionated heparin, low molecular weight heparin, bivalirudin, aspirin, glycoprotein IIb/IIIa inhibitors, and clopidogrel. Data supporting each strategy are presented as are dosing recommendations. © 2013 Blackwell Publishing Ltd.
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