Overview
Dr. Permar's work focuses on the development of vaccines to prevent vertical transmission of neonatal viral pathogens. She has utilized the nonhuman primate model of HIV/AIDS to characterize the virus-specific immune responses and virus evolution in breast milk and develop a maternal vaccine regimen for protection against breast milk transmission of HIV. In addition, Dr. Permar's lab has advanced the understanding of HIV-specific immune responses and virus evolution in vertically-transmitting and nontransmitting HIV-infected women, defining maternal immune responses that may protect against neonatal transmission of HIV. Importantly, Dr. Permar has established a nonhuman primate model of congenital CMV infection adn is using this model to establish the maternal immune responses that are necessary for protection against placental virus transmission. Finally, Dr. Permar is studying the impact and prevention of postnatal CMV transmission in preterm infants.
Current Appointments & Affiliations
Adjunct Professor in the Department of Pathology
·
2021 - Present
Pathology,
Clinical Science Departments
Associate Dean for Physician-Scientist Development
·
2018 - Present
School of Medicine
Affiliate, Duke Global Health Institute
·
2013 - Present
Duke Global Health Institute,
University Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
Initiatives
Education, Training & Certifications
Harvard Medical School ·
2004
M.D.
Johns Hopkins University ·
2004
Ph.D.