Scholars@Duke
Nikolai Petrovich Skiba

Nikolai Petrovich Skiba

Associate Professor of Ophthalmology
Ophthalmology
Box 3802 Med Ctr, Durham, NC 27710
Wadsworth Bldg, Durham, NC 27710
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Overview

My research focuses on applying mass spectrometry based proteomics to study proteins in eye tissues, cells and sub-cellular compartments to understand mechanisms of vision. An important aspect of my research is to identify proteins in different compartments of retinal photoreceptor cells, their amount and modification status at different cell states defined by the light conditions, genotype, disease etc. This information can be valuable in understanding molecular mechanisms of vision and biology of the photoreceptor cell. Another important aspect of my research is to assist basic scientist and clinicians in our department in their proteomic needs which include identification of proteins and other biomolecules in a given biological sample, detection of protein post-translational modifications and sequence variations, elucidation of protein-protein interactions and also characterization of changes in the protein concentration and composition in a biological sample at different conditions.

Current Appointments & Affiliations

Associate Professor of Ophthalmology · 2021 - Present Ophthalmology, Clinical Science Departments

Education, Training & Certifications

Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry (Russia) · 1986 Ph.D.
Lomonosov Moscow State Universty (Russia) · 1978 B.S.