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Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study

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Silverman, SL; Siris, E; Kendler, DL; Belazi, D; Brown, JP; Gold, DT; Lewiecki, EM; Papaioannou, A; Simonelli, C; Ferreira, I; Dakin, P; Ho, P ...
Published in: Osteoporosis International
September 19, 2014

Summary: To determine persistence with subcutaneous denosumab every 6 months in women being treated for osteoporosis, we conducted a single-arm prospective, observational study in the United States and Canada. Among 935 patients enrolled, 12-month persistence was 82 %, with 66 patients (7 %) reporting serious adverse events and 19 patients (2 %) reporting fractures.

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Published In

Osteoporosis International

DOI

EISSN

1433-2965

ISSN

0937-941X

Publication Date

September 19, 2014

Publisher

Springer-Verlag London Ltd

Related Subject Headings

  • Endocrinology & Metabolism
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering
 

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Silverman, S. L., Siris, E., Kendler, D. L., Belazi, D., Brown, J. P., Gold, D. T., … Recknor, C. (2014). Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study (Accepted). In Osteoporosis International. Springer-Verlag London Ltd. https://doi.org/10.1007/s00198-014-2871-6
Silverman, S. L., E. Siris, D. L. Kendler, D. Belazi, J. P. Brown, D. T. Gold, E. M. Lewiecki, et al. “Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study (Accepted).” In Osteoporosis International. Springer-Verlag London Ltd, 2014. https://doi.org/10.1007/s00198-014-2871-6.
Silverman SL, Siris E, Kendler DL, Belazi D, Brown JP, Gold DT, et al. Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study (Accepted). In: Osteoporosis International. Springer-Verlag London Ltd; 2014.
Silverman, S. L., et al. “Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study (Accepted).” Osteoporosis International, Springer-Verlag London Ltd, 2014. Scopus, doi:10.1007/s00198-014-2871-6.
Silverman SL, Siris E, Kendler DL, Belazi D, Brown JP, Gold DT, Lewiecki EM, Papaioannou A, Simonelli C, Ferreira I, Balasubramanian A, Dakin P, Ho P, Siddhanti S, Stolshek B, Recknor C. Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study (Accepted). Osteoporosis International. Springer-Verlag London Ltd; 2014.
Journal cover image

Published In

Osteoporosis International

DOI

EISSN

1433-2965

ISSN

0937-941X

Publication Date

September 19, 2014

Publisher

Springer-Verlag London Ltd

Related Subject Headings

  • Endocrinology & Metabolism
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering