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Stereotactic body radiotherapy: a critical review for nonradiation oncologists.

Publication ,  Journal Article
Kirkpatrick, JP; Kelsey, CR; Palta, M; Cabrera, AR; Salama, JK; Patel, P; Perez, BA; Lee, J; Yin, F-F
Published in: Cancer
April 1, 2014

Stereotactic body radiotherapy (SBRT) involves the treatment of extracranial primary tumors or metastases with a few, high doses of ionizing radiation. In SBRT, tumor kill is maximized and dose to surrounding tissue is minimized, by precise and accurate delivery of multiple radiation beams to the target. This is particularly challenging, because extracranial lesions often move with respiration and are irregular in shape, requiring careful treatment planning and continual management of this motion and patient position during irradiation. This review presents the rationale, process workflow, and technology for the safe and effective administration of SBRT, as well as the indications, outcome, and limitations for this technique in the treatment of lung cancer, liver cancer, and metastatic disease.

Duke Scholars

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Published In

Cancer

DOI

EISSN

1097-0142

Publication Date

April 1, 2014

Volume

120

Issue

7

Start / End Page

942 / 954

Location

United States

Related Subject Headings

  • Radiosurgery
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • 4206 Public health
  • 3211 Oncology and carcinogenesis
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
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ICMJE
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Kirkpatrick, J. P., Kelsey, C. R., Palta, M., Cabrera, A. R., Salama, J. K., Patel, P., … Yin, F.-F. (2014). Stereotactic body radiotherapy: a critical review for nonradiation oncologists. Cancer, 120(7), 942–954. https://doi.org/10.1002/cncr.28515
Kirkpatrick, John P., Christopher R. Kelsey, Manisha Palta, Alvin R. Cabrera, Joseph K. Salama, Pretesh Patel, Bradford A. Perez, Jason Lee, and Fang-Fang Yin. “Stereotactic body radiotherapy: a critical review for nonradiation oncologists.Cancer 120, no. 7 (April 1, 2014): 942–54. https://doi.org/10.1002/cncr.28515.
Kirkpatrick JP, Kelsey CR, Palta M, Cabrera AR, Salama JK, Patel P, et al. Stereotactic body radiotherapy: a critical review for nonradiation oncologists. Cancer. 2014 Apr 1;120(7):942–54.
Kirkpatrick, John P., et al. “Stereotactic body radiotherapy: a critical review for nonradiation oncologists.Cancer, vol. 120, no. 7, Apr. 2014, pp. 942–54. Pubmed, doi:10.1002/cncr.28515.
Kirkpatrick JP, Kelsey CR, Palta M, Cabrera AR, Salama JK, Patel P, Perez BA, Lee J, Yin F-F. Stereotactic body radiotherapy: a critical review for nonradiation oncologists. Cancer. 2014 Apr 1;120(7):942–954.
Journal cover image

Published In

Cancer

DOI

EISSN

1097-0142

Publication Date

April 1, 2014

Volume

120

Issue

7

Start / End Page

942 / 954

Location

United States

Related Subject Headings

  • Radiosurgery
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • 4206 Public health
  • 3211 Oncology and carcinogenesis
  • 1117 Public Health and Health Services
  • 1112 Oncology and Carcinogenesis