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Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care?

Publication ,  Journal Article
Maciejewski, ML; Bosworth, HB; Olsen, MK; Smith, VA; Edelman, D; Powers, BJ; Kaufman, MA; Oddone, EZ; Jackson, GL
Published in: Circ Cardiovasc Qual Outcomes
March 2014

BACKGROUND: Hypertension self-management has been shown to improve systolic blood pressure (BP) control, but longer-term economic and clinical impacts are unknown. The purpose of this article is to examine clinical and economic outcomes 18 months after completion of a hypertension self-management trial. METHODS AND RESULTS: This study is a follow-up analysis of an 18-month, 4-arm, hypertension self-management trial of 591 veterans with hypertension who were randomized to usual care or 1 of 3 interventions. Clinic-derived systolic blood pressure obtained before, during, and after the trial were estimated using linear mixed models. Inpatient admissions, outpatient expenditures, and total expenditures were estimated using generalized estimating equations. The 3 telephone-based interventions were nurse-administered health behavior promotion, provider-administered medication adjustments based on hypertension treatment guidelines, or a combination of both. Intervention calls were triggered by home BP values transmitted via telemonitoring devices. Clinical and economic outcomes were examined 12 months before, 18 months during, and 18 months after trial completion. Compared with usual care, patients randomized to the combined arm had greater improvement in proportion of BP control during and after the 18-month trial and estimated proportion of BP control improved 18 months after trial completion for patients in the behavioral and medication management arms. Among the patients with inadequate baseline BP control, estimated mean systolic BP was significantly lower in the combined arm as compared with usual care during and after the 18-month trial. Utilization and expenditure trends were similar for patients in all 4 arms. CONCLUSIONS: Behavioral and medication management can generate systolic BP improvements that are sustained 18 months after trial completion. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00237692.

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Published In

Circ Cardiovasc Qual Outcomes

DOI

EISSN

1941-7705

Publication Date

March 2014

Volume

7

Issue

2

Start / End Page

269 / 275

Location

United States

Related Subject Headings

  • United States
  • Treatment Outcome
  • Time Factors
  • Telemedicine
  • Self Care
  • Middle Aged
  • Medication Adherence
  • Male
  • Hypertension
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
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Maciejewski, M. L., Bosworth, H. B., Olsen, M. K., Smith, V. A., Edelman, D., Powers, B. J., … Jackson, G. L. (2014). Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care? Circ Cardiovasc Qual Outcomes, 7(2), 269–275. https://doi.org/10.1161/CIRCOUTCOMES.113.000309
Maciejewski, Matthew L., Hayden B. Bosworth, Maren K. Olsen, Valerie A. Smith, David Edelman, Benjamin J. Powers, Miriam A. Kaufman, Eugene Z. Oddone, and George L. Jackson. “Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care?Circ Cardiovasc Qual Outcomes 7, no. 2 (March 2014): 269–75. https://doi.org/10.1161/CIRCOUTCOMES.113.000309.
Maciejewski ML, Bosworth HB, Olsen MK, Smith VA, Edelman D, Powers BJ, et al. Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care? Circ Cardiovasc Qual Outcomes. 2014 Mar;7(2):269–75.
Maciejewski, Matthew L., et al. “Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care?Circ Cardiovasc Qual Outcomes, vol. 7, no. 2, Mar. 2014, pp. 269–75. Pubmed, doi:10.1161/CIRCOUTCOMES.113.000309.
Maciejewski ML, Bosworth HB, Olsen MK, Smith VA, Edelman D, Powers BJ, Kaufman MA, Oddone EZ, Jackson GL. Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care? Circ Cardiovasc Qual Outcomes. 2014 Mar;7(2):269–275.

Published In

Circ Cardiovasc Qual Outcomes

DOI

EISSN

1941-7705

Publication Date

March 2014

Volume

7

Issue

2

Start / End Page

269 / 275

Location

United States

Related Subject Headings

  • United States
  • Treatment Outcome
  • Time Factors
  • Telemedicine
  • Self Care
  • Middle Aged
  • Medication Adherence
  • Male
  • Hypertension
  • Humans