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A call to standardize preanalytic data elements for biospecimens.

Publication ,  Journal Article
Robb, JA; Gulley, ML; Fitzgibbons, PL; Kennedy, MF; Cosentino, LM; Washington, K; Dash, RC; Branton, PA; Jewell, SD; Lapham, RL
Published in: Arch Pathol Lab Med
April 2014

CONTEXT: Biospecimens must have appropriate clinical annotation (data) to ensure optimal quality for both patient care and research. Clinical preanalytic variables are the focus of this study. OBJECTIVE: To define the essential preanalytic variables (data fields) that should be attached to every collected biospecimen and to provide a complete list of such variables, along with their relative importance, which can vary, depending on downstream use, institutional needs, and information technology capabilities. DESIGN: The College of American Pathologists Diagnostic Intelligence and Health Information Technology Committee sponsored a Biorepository Working Group to develop a ranked list of the preanalytic variables for annotating biospecimens. Members of the working group were experts in anatomic, clinical, and molecular pathology; biobanking; medical informatics; and accreditation. Several members had experience with federal government programs, such as the National Cancer Institute's Biospecimens and Biorepository Branch and the National Cancer Institute's Community Cancer Center Program. Potential preanalytic variables were identified and ranked along with available supporting evidence, definitions, and potential negative effects if the variable was not attached to the biospecimen. Additional national and international stakeholders reviewed the draft manuscript. RESULTS: The ranked listing of 170 preanalytic variables produced can be used as a guide for site-specific implementation into patient care and/or research biorepository processes. Conclusions.-In our collective experience, it is often difficult to choose which of the many preanalytic variables to attach to any specific set of biospecimens used for patient care and/or research. The provided ranked list should aid in the selection of preanalytic variables for a given biospecimen collection.

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Published In

Arch Pathol Lab Med

DOI

EISSN

1543-2165

Publication Date

April 2014

Volume

138

Issue

4

Start / End Page

526 / 537

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Pathology
  • Pathology
  • Humans
  • Biological Specimen Banks
  • Advisory Committees
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Robb, J. A., Gulley, M. L., Fitzgibbons, P. L., Kennedy, M. F., Cosentino, L. M., Washington, K., … Lapham, R. L. (2014). A call to standardize preanalytic data elements for biospecimens. Arch Pathol Lab Med, 138(4), 526–537. https://doi.org/10.5858/arpa.2013-0250-CP
Robb, James A., Margaret L. Gulley, Patrick L. Fitzgibbons, Mary F. Kennedy, L Mark Cosentino, Kay Washington, Rajesh C. Dash, Philip A. Branton, Scott D. Jewell, and Rosanna L. Lapham. “A call to standardize preanalytic data elements for biospecimens.Arch Pathol Lab Med 138, no. 4 (April 2014): 526–37. https://doi.org/10.5858/arpa.2013-0250-CP.
Robb JA, Gulley ML, Fitzgibbons PL, Kennedy MF, Cosentino LM, Washington K, et al. A call to standardize preanalytic data elements for biospecimens. Arch Pathol Lab Med. 2014 Apr;138(4):526–37.
Robb, James A., et al. “A call to standardize preanalytic data elements for biospecimens.Arch Pathol Lab Med, vol. 138, no. 4, Apr. 2014, pp. 526–37. Pubmed, doi:10.5858/arpa.2013-0250-CP.
Robb JA, Gulley ML, Fitzgibbons PL, Kennedy MF, Cosentino LM, Washington K, Dash RC, Branton PA, Jewell SD, Lapham RL. A call to standardize preanalytic data elements for biospecimens. Arch Pathol Lab Med. 2014 Apr;138(4):526–537.

Published In

Arch Pathol Lab Med

DOI

EISSN

1543-2165

Publication Date

April 2014

Volume

138

Issue

4

Start / End Page

526 / 537

Location

United States

Related Subject Headings

  • United States
  • Societies, Medical
  • Pathology
  • Pathology
  • Humans
  • Biological Specimen Banks
  • Advisory Committees
  • 3202 Clinical sciences
  • 1103 Clinical Sciences