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Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the BacT/alert blood culture system.

Publication ,  Journal Article
Doern, CD; Mirrett, S; Halstead, D; Abid, J; Okada, P; Reller, LB
Published in: J Clin Microbiol
June 2014

We conducted a controlled clinical comparison of PF Plus, the new pediatric medium with adsorbent polymeric beads, versus the charcoal-containing PF medium in the BacT/Alert blood culture system. A total of 2,381 pediatric cultures were enrolled, and 1,703 (71.5%) were deemed to be compliant and acceptable for analysis. Seventy-two cultures (4.2%) had a positive result with 80 clinically significant microorganisms. The results showed that the PF Plus medium yielded more clinically significant microorganisms than the BacT/Alert system (P < 0.05). In addition, the PF Plus bottle yielded positive results an average of 5.0 h earlier than the PF bottle for compliant clinically significant cultures (18.3 h versus 23.2 h, P = 0.004). PF Plus is an improved medium for detecting microorganisms that cause pediatric bloodstream infections.

Duke Scholars

Published In

J Clin Microbiol

DOI

EISSN

1098-660X

Publication Date

June 2014

Volume

52

Issue

6

Start / End Page

1898 / 1900

Location

United States

Related Subject Headings

  • Time Factors
  • Sepsis
  • Sensitivity and Specificity
  • Microbiology
  • Microbiological Techniques
  • Male
  • Infant, Newborn
  • Infant
  • Humans
  • Female
 

Citation

APA
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Doern, C. D., Mirrett, S., Halstead, D., Abid, J., Okada, P., & Reller, L. B. (2014). Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the BacT/alert blood culture system. J Clin Microbiol, 52(6), 1898–1900. https://doi.org/10.1128/JCM.00175-14
Doern, Christopher D., Stanley Mirrett, Diane Halstead, Joan Abid, Pamela Okada, and L Barth Reller. “Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the BacT/alert blood culture system.J Clin Microbiol 52, no. 6 (June 2014): 1898–1900. https://doi.org/10.1128/JCM.00175-14.
Doern, Christopher D., et al. “Controlled clinical comparison of new pediatric medium with adsorbent polymeric beads (PF Plus) versus charcoal-containing PF medium in the BacT/alert blood culture system.J Clin Microbiol, vol. 52, no. 6, June 2014, pp. 1898–900. Pubmed, doi:10.1128/JCM.00175-14.

Published In

J Clin Microbiol

DOI

EISSN

1098-660X

Publication Date

June 2014

Volume

52

Issue

6

Start / End Page

1898 / 1900

Location

United States

Related Subject Headings

  • Time Factors
  • Sepsis
  • Sensitivity and Specificity
  • Microbiology
  • Microbiological Techniques
  • Male
  • Infant, Newborn
  • Infant
  • Humans
  • Female