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One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes.

Publication ,  Journal Article
Brehm, BJ; Lattin, BL; Summer, SS; Boback, JA; Gilchrist, GM; Jandacek, RJ; D'Alessio, DA
Published in: Diabetes Care
February 2009

OBJECTIVE: The purpose of this study was to compare the effects of high-monounsaturated fatty acid (MUFA) and high-carbohydrate (CHO) diets on body weight and glycemic control in men and women with type 2 diabetes. RESEARCH DESIGN AND METHODS: Overweight/obese participants with type 2 diabetes (n = 124, age = 56.5 +/- 0.8 years, BMI = 35.9 +/- 0.3 kg/m2, and A1C = 7.3 +/- 0.1%) were randomly assigned to 1 year of a high-MUFA or high-CHO diet. Anthropometric and metabolic parameters were assessed at baseline and after 4, 8, and 12 months of dieting. RESULTS: Baseline characteristics were similar between the treatment groups. The overall retention rate for 1 year was 77% (69% for the high-MUFA group and 84% for the high-CHO group; P = 0.06). Based on food records, both groups had similar energy intake but a significant difference in MUFA intake. Both groups had similar weight loss over 1 year (-4.0 +/- 0.8 vs. -3.8 +/- 0.6 kg) and comparable improvement in body fat, waist circumference, diastolic blood pressure, HDL cholesterol, A1C, and fasting glucose and insulin. There were no differences in these parameters between the groups. A follow-up assessment of a subset of participants (n = 36) was conducted 18 months after completion of the 52-week diet. These participants maintained their weight loss and A1C during the follow-up period. CONCLUSIONS: In individuals with type 2 diabetes, high-MUFA diets are an alternative to conventional lower-fat, high-CHO diets with comparable beneficial effects on body weight, body composition, cardiovascular risk factors, and glycemic control.

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Published In

Diabetes Care

DOI

EISSN

1935-5548

Publication Date

February 2009

Volume

32

Issue

2

Start / End Page

215 / 220

Location

United States

Related Subject Headings

  • Patient Selection
  • Patient Compliance
  • Overweight
  • Middle Aged
  • Hypoglycemic Agents
  • Humans
  • Feeding Behavior
  • Fatty Acids, Monounsaturated
  • Endocrinology & Metabolism
  • Dietary Fats
 

Citation

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Chicago
ICMJE
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Brehm, B. J., Lattin, B. L., Summer, S. S., Boback, J. A., Gilchrist, G. M., Jandacek, R. J., & D’Alessio, D. A. (2009). One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes. Diabetes Care, 32(2), 215–220. https://doi.org/10.2337/dc08-0687
Brehm, Bonnie J., Barbara L. Lattin, Suzanne S. Summer, Jane A. Boback, Gina M. Gilchrist, Ronald J. Jandacek, and David A. D’Alessio. “One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes.Diabetes Care 32, no. 2 (February 2009): 215–20. https://doi.org/10.2337/dc08-0687.
Brehm BJ, Lattin BL, Summer SS, Boback JA, Gilchrist GM, Jandacek RJ, et al. One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes. Diabetes Care. 2009 Feb;32(2):215–20.
Brehm, Bonnie J., et al. “One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes.Diabetes Care, vol. 32, no. 2, Feb. 2009, pp. 215–20. Pubmed, doi:10.2337/dc08-0687.
Brehm BJ, Lattin BL, Summer SS, Boback JA, Gilchrist GM, Jandacek RJ, D’Alessio DA. One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes. Diabetes Care. 2009 Feb;32(2):215–220.

Published In

Diabetes Care

DOI

EISSN

1935-5548

Publication Date

February 2009

Volume

32

Issue

2

Start / End Page

215 / 220

Location

United States

Related Subject Headings

  • Patient Selection
  • Patient Compliance
  • Overweight
  • Middle Aged
  • Hypoglycemic Agents
  • Humans
  • Feeding Behavior
  • Fatty Acids, Monounsaturated
  • Endocrinology & Metabolism
  • Dietary Fats