Skip to main content

Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals.

Publication ,  Journal Article
Owen, OE; Mozzoli, MA; Smalley, KJ; Kavle, EC; D'Alessio, DA
Published in: Am J Clin Nutr
March 1992

Oxidative and nonoxidative macronutrient disposal rates were measured in lean and obese males randomly fed mixed meals containing 0, 33, 67, 100, and 134 kJ/kg fat-free mass (0, 8, 16, 24, and 32 kcal/kg). Body composition, preprandial and postprandial energy expenditure, and macronutrient concentrations in the extracellular space were measured. Relationships among carbohydrate, fat, and protein disposal rates; body weight; and body composition were examined. Oxidative and nonoxidative disposals of macronutrients were not different between the lean and obese groups. Glucose was preferentially oxidized and fat was preferentially stored after nutrient ingestion. Macronutrient storage increased linearly with caloric intake. Oxidative and nonoxidative macronutrient disposals were completed within 8 h after ingesting the meals. Serum insulin concentrations rose to 3000-6000 pmol/L in two obese men after their two largest meals. Eight hours after nutrient ingestion, concentrations of macronutrient substrates, metabolic products, and insulin were indistinguishable from preprandial values.

Duke Scholars

Published In

Am J Clin Nutr

DOI

ISSN

0002-9165

Publication Date

March 1992

Volume

55

Issue

3

Start / End Page

630 / 636

Location

United States

Related Subject Headings

  • Oxidation-Reduction
  • Obesity
  • Nutrition & Dietetics
  • Male
  • Insulin
  • Humans
  • Glucose
  • Food
  • Fatty Acids, Nonesterified
  • Extracellular Space
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Owen, O. E., Mozzoli, M. A., Smalley, K. J., Kavle, E. C., & D’Alessio, D. A. (1992). Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals. Am J Clin Nutr, 55(3), 630–636. https://doi.org/10.1093/ajcn/55.3.630
Owen, O. E., M. A. Mozzoli, K. J. Smalley, E. C. Kavle, and D. A. D’Alessio. “Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals.Am J Clin Nutr 55, no. 3 (March 1992): 630–36. https://doi.org/10.1093/ajcn/55.3.630.
Owen OE, Mozzoli MA, Smalley KJ, Kavle EC, D’Alessio DA. Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals. Am J Clin Nutr. 1992 Mar;55(3):630–6.
Owen, O. E., et al. “Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals.Am J Clin Nutr, vol. 55, no. 3, Mar. 1992, pp. 630–36. Pubmed, doi:10.1093/ajcn/55.3.630.
Owen OE, Mozzoli MA, Smalley KJ, Kavle EC, D’Alessio DA. Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals. Am J Clin Nutr. 1992 Mar;55(3):630–636.

Published In

Am J Clin Nutr

DOI

ISSN

0002-9165

Publication Date

March 1992

Volume

55

Issue

3

Start / End Page

630 / 636

Location

United States

Related Subject Headings

  • Oxidation-Reduction
  • Obesity
  • Nutrition & Dietetics
  • Male
  • Insulin
  • Humans
  • Glucose
  • Food
  • Fatty Acids, Nonesterified
  • Extracellular Space