Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy?
Publication
, Journal Article
Melton, MS; Nielsen, KC; Tucker, M; Klein, SM; Gan, TJ
Published in: Anesthesiol Clin
June 2014
In a growing outpatient surgical population, postdischarge nausea and vomiting (PDNV) is unfortunately a common and costly anesthetic complication. Identification of risk factors for both postoperative nausea and vomiting and PDNV is the hallmark of prevention and management. New pharmacologic interventions with extended duration of action, including palonosetron and aprepritant, may prove to be more efficacious.
Duke Scholars
Published In
Anesthesiol Clin
DOI
ISSN
1932-2275
Publication Date
June 2014
Volume
32
Issue
2
Start / End Page
505 / 516
Location
United States
Related Subject Headings
- Time Factors
- Serotonin Antagonists
- Quinuclidines
- Postoperative Nausea and Vomiting
- Patient Discharge
- Palonosetron
- Neurokinin-1 Receptor Antagonists
- Isoquinolines
- Humans
- Antiemetics
Citation
APA
Chicago
ICMJE
MLA
NLM
Melton, M. S., Nielsen, K. C., Tucker, M., Klein, S. M., & Gan, T. J. (2014). Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy? Anesthesiol Clin, 32(2), 505–516. https://doi.org/10.1016/j.anclin.2014.02.004
Melton, M Stephen, Karen C. Nielsen, Marcy Tucker, Stephen M. Klein, and Tong J. Gan. “Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy?” Anesthesiol Clin 32, no. 2 (June 2014): 505–16. https://doi.org/10.1016/j.anclin.2014.02.004.
Melton MS, Nielsen KC, Tucker M, Klein SM, Gan TJ. Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy? Anesthesiol Clin. 2014 Jun;32(2):505–16.
Melton, M. Stephen, et al. “Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy?” Anesthesiol Clin, vol. 32, no. 2, June 2014, pp. 505–16. Pubmed, doi:10.1016/j.anclin.2014.02.004.
Melton MS, Nielsen KC, Tucker M, Klein SM, Gan TJ. Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy? Anesthesiol Clin. 2014 Jun;32(2):505–516.
Published In
Anesthesiol Clin
DOI
ISSN
1932-2275
Publication Date
June 2014
Volume
32
Issue
2
Start / End Page
505 / 516
Location
United States
Related Subject Headings
- Time Factors
- Serotonin Antagonists
- Quinuclidines
- Postoperative Nausea and Vomiting
- Patient Discharge
- Palonosetron
- Neurokinin-1 Receptor Antagonists
- Isoquinolines
- Humans
- Antiemetics