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Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion: a single institutional experience.

Publication ,  Journal Article
Adogwa, O; Fatemi, P; Perez, E; Moreno, J; Gazcon, GC; Gokaslan, ZL; Cheng, J; Gottfried, O; Bagley, CA
Published in: Spine J
December 1, 2014

BACKGROUND CONTEXT: Wound dehiscence and surgical site infections (SSIs) can have a profound impact on patients as they often require hospital readmission, additional surgical interventions, lengthy intravenous antibiotic administration, and delayed rehabilitation. Negative pressure wound therapy (NPWT) exposes the wound site to negative pressure, resulting in the improvement of blood supply, removal of excess fluid, and stimulation of cellular proliferation of granulation tissue. PURPOSE: To assess the incidence of wound infection and dehiscence in patients undergoing long-segment thoracolumbar fusion before and after the routine use of NPWT. STUDY DESIGN: Retrospective study. PATIENT SAMPLE: One hundred sixty patients undergoing long-segment thoracolumbar spine fusions were included in this study. OUTCOME MEASURES: Postoperative incidence of wound infection and dehiscence. METHODS: All adult patients undergoing thoracolumbar fusion for spinal deformity over a 6-year period at Duke University Medical Center by the senior author (CB) were included in this study. In 2012, a categorical change was made by the senior author (CB) that included the postoperative routine use of incisional NPWT devices after primary wound closure in all long-segment spine fusions. Before 2012, NPWT was not used. After primary wound closure, a negative pressure device is contoured to the size of the incision and placed over the incision site for 3 postoperative days. We retrospectively review the first 46 cases in which NPWT was used and compared them with the immediately preceding 114 cases to assess the incidence of wound infection and dehiscence. RESULTS: One hundred sixty (NPWT: 46 cases, non-NPWT: 114 cases) long-segment thoracolumbar spine fusions were performed for deformity correction. Baseline characteristics were similar between both cohorts. Compared with the non-NPWT cohort, a 50% decrease in the incidence of wound dehiscence was observed in the NPWT patient cohort (6.38% vs. 12.28%, p=.02). Similarly, compared with the non-NPWT cohort, the incidence of postoperative SSIs was significantly decreased in the NPWT cohort (10.63% vs. 14.91%, p=.04). CONCLUSIONS: Routine use of incisional NPWT was associated with a significant reduction in the incidence of postoperative wound infection and dehiscence.

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Published In

Spine J

DOI

EISSN

1878-1632

Publication Date

December 1, 2014

Volume

14

Issue

12

Start / End Page

2911 / 2917

Location

United States

Related Subject Headings

  • Surgical Wound Infection
  • Spinal Fusion
  • Orthopedics
  • Negative-Pressure Wound Therapy
  • Middle Aged
  • Male
  • Humans
  • Female
  • Case-Control Studies
  • Aged
 

Citation

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Adogwa, O., Fatemi, P., Perez, E., Moreno, J., Gazcon, G. C., Gokaslan, Z. L., … Bagley, C. A. (2014). Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion: a single institutional experience. Spine J, 14(12), 2911–2917. https://doi.org/10.1016/j.spinee.2014.04.011
Adogwa, Owoicho, Parastou Fatemi, Edgar Perez, Jessica Moreno, Gustavo Chagoya Gazcon, Ziya L. Gokaslan, Joseph Cheng, Oren Gottfried, and Carlos A. Bagley. “Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion: a single institutional experience.Spine J 14, no. 12 (December 1, 2014): 2911–17. https://doi.org/10.1016/j.spinee.2014.04.011.
Adogwa, Owoicho, et al. “Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion: a single institutional experience.Spine J, vol. 14, no. 12, Dec. 2014, pp. 2911–17. Pubmed, doi:10.1016/j.spinee.2014.04.011.
Adogwa O, Fatemi P, Perez E, Moreno J, Gazcon GC, Gokaslan ZL, Cheng J, Gottfried O, Bagley CA. Negative pressure wound therapy reduces incidence of postoperative wound infection and dehiscence after long-segment thoracolumbar spinal fusion: a single institutional experience. Spine J. 2014 Dec 1;14(12):2911–2917.
Journal cover image

Published In

Spine J

DOI

EISSN

1878-1632

Publication Date

December 1, 2014

Volume

14

Issue

12

Start / End Page

2911 / 2917

Location

United States

Related Subject Headings

  • Surgical Wound Infection
  • Spinal Fusion
  • Orthopedics
  • Negative-Pressure Wound Therapy
  • Middle Aged
  • Male
  • Humans
  • Female
  • Case-Control Studies
  • Aged